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KMID : 0387919930040010009
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Korean Journal of Cytopathology
1993 Volume.4 No. 1 p.9 ~ p.15
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Usefulness of Intraoperative Fine Needle Aspiration of Pancreatic lesions
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Abstract
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The aim of the present study is to demonstrate the usefulness of intraoperative fine needle aspiration(FNA) of pancreatic lesions in 30 patients. A conclusive diagnosis was done in 27 patients and the diagnoses of three patients were
deferred.
No complications followed the procedure. Based on histologic findings of the resected specimens in 20 cases and of cell blocks in 10 cases, the final diagnoses were adenocarcinoma in 19 cases, chronic pancreatitis in nine cases and
tuberculosis
in two cases. The sensitivity, specificity and diagnostic accuracy were 95%, 100% and 96% resepectively and there were no false positives. The smear of aspirate was stained with toluidine blue and examined by light microscope. The
presence of there-dimensional clusters of disoriented cells and the increased nuclear/cytoplasmic ratio with large prominent nucleoli were the most helpful criteria for a diagnosis of malignancy in the pancreas. The
intraoperative FNA of pancreatic lesions was considered as simple, safe, and highly specific and sensitive tool in differentiating benign from malignant lesions The intraoperative FNA can be recommended as the first tool of choice of
intraoperative
diagnostic procedure in lesions of the pancreas.
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KEYWORD
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